Last edited by Kajidal
Wednesday, July 22, 2020 | History

7 edition of Polyamine cell signaling found in the catalog.

Polyamine cell signaling

physiology, pharmacology, and cancer research

  • 216 Want to read
  • 9 Currently reading

Published by Humana Press in Totowa, N.J .
Written in English

    Subjects:
  • Polyamines,
  • Polyamines in the body,
  • Cellular signal transduction,
  • Polyamines,
  • Cell Physiology,
  • Neoplasms,
  • Signal Transduction

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Jian-Ying Wang, Robert A. Casero Jr.
    ContributionsWang, J.-Y., Casero, Robert Anthony.
    Classifications
    LC ClassificationsQP801.P638 P58 2006
    The Physical Object
    Paginationp. ;
    ID Numbers
    Open LibraryOL3417144M
    ISBN 101588296253
    LC Control Number2005033438

    Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines, as well as providing the underlying conceptual basis and knowledge regarding potential therapeutic-targeting polyamines and polyamine metabolism leading to the development of new therapeutic approaches for cancers and.   Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living s:

      The polyamine metabolic pathway plays an especially important role in epithelial cancer progression. The WNT signaling pathway is a major pathway governing epithelial development. Its normal functioning is lost during cancer progression. The key players in WNT signaling are the adenomatous polyposis coli (APC) and β-catenin proteins.   To which extent the affinity of polyamines for ATP (or potentially other energetic nucleotides relevant to cell signaling, such as guanosine 5′-triphosphate) is central to the regulation of cell signaling by these molecules remains to be clarified. Polyamines favor the activation of β .

      The cell signaling make simple for every student and physician; a good book for a fast understanding about mechanisms and biochemical solutions of cell communications (cell-to-cell and inside-cell). However, sometimes it is too schematic and is easy lose the concepts of a complex communication s: 7. Polyamine-Dependent Early Cellular Signals and Cell Proliferation Oredsson, Stina LU p Mark; Abstract When a resting cell is awakened to enter the cell cycle by mitogenic stimulation, a complex molecular machinery involving positive and negative regulation of cell-cycle progression is initiated. Part of the machinery is quite well-known.


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Polyamine cell signaling Download PDF EPUB FB2

Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines, as well as providing the underlying conceptual basis and knowledge regarding potential therapeutic-targeting polyamines and polyamine metabolism leading to the development of new therapeutic approaches for cancers and Format: Hardcover.

Available in: ines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological Due to COVID, orders may be delayed. Thank you for your patience. Book Annex Membership Educators Gift Cards Stores & Events HelpPrice: $ Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines, as well as providing the underlying conceptual basis and knowledge regarding potential therapeutic-targeting polyamines and polyamine metabolism leading to the development of new therapeutic approaches for cancers and.

Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple.

Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions.

An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und. Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell–Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to.

Save on Polyamine Cell Signaling by. Shop your textbooks from Zookal AU today. Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions.

An increasing body of evidence indicates that the. Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses.

A model depicting the PA-signaling processes in leaf senescence is shown in Fig. Download: Download full-size image; Fig. A work-in-progress model depicting polyamine-associated signaling in dark-induced senescence. Dark-induced senescence involves a series of transformations at the cytological, biochemical, and genetic levels.

Polyamine analogues. The critical role of polyamines in cell growth has led to the development of a number of agents that interfere with polyamine metabolism.

These agents are used in cancer therapy. Polyamine analogues upregulate p53 in a cell leading to restriction of proliferation and apoptosis.

Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines, as well as providing.

ChIP was performed using the SimpleCHIP enzymatic chromatin immunoprecipitation kit (Cell Signaling Technology cat. ) according to the manufacturer’s instruction with minor modifications. In brief, primary mouse keratinocytes were harvested and cross-linked with 1% (v/v) formaldehyde for 10 min at RT.

Polyamine cell signaling. T otowa: Humana Press, p. A obra apresenta uma abordagem científica sobre as fun- Book. Polyamine cell signaling: Polyamine cell signaling.

January   Free Online Library: Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research.(Brief Article, Book Review) by "SciTech Book News"; Publishing industry Library and information science Science and technology, general Books Book reviews.

Printer Friendly. 24, articles and books. The diversity of biological research in the polyamine field is the subject of an excellent book (2). Keeping in mind the diverse nature of polyamine distribution and function, it is reasonable to assume that carefully designed polyamine analogs could have the potential to disrupt polyamine metabolism, and thus such agents have been investigated.

Inhibitors of polyamine biosynthesis and inducers of their catabolism have been evaluated as antitumor drugs, however, their efficacy and safety remain controversial. Our goal was to investigate if drug-induced modulation of polyamine metabolism plays a role in dedifferentiation using differentiated human hepatocyte-like HepaRG cell cultures.

Decreases of polyamine levels interfere with cell growth, leading to G1 arrest in S. cerevisiae and to embryonic lethality in mice. Abnormally high levels of polyamines appear to be toxic, causing apoptosis in mammalian cells. Polyamine content is increased in many cancers arising from epithelial tissues, such as skin and colon.

Summary: Suitable for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. This book covers various findings relevant to cellular and molecular functions of polyamines. It also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting polyamines and polyamine metabolism.

Proliferation, Differentiation, and Apoptosis. Polyamines are essential for cell proliferation. Polyamine content is higher in rapidly growing tissues, and regenerative and growth-promoting hormonal stimuli enhance polyamine synthesis and content (15 – 17).Treatment of cultured cells with ODC inhibitors such as α-difluoromethylornithine (DFMO) led to a virtually complete loss of putrescine.

The Xanthomonas campestris pv vesicatoria ([ Xcv ][1]) effector AvrBsT induces a hypersensitive cell death in pepper (Capsicum annuum). However, the molecular mechanisms underlying AvrBsT - triggered cell death are not fully understood. Here, we identified pepper arginine decarboxylase (CaADC1) as an AvrBsT-interacting protein, which is early and strongly induced in incompatible .Polyamine phone Signaling: body structure, Pharmacology, and melanoma examine offers present cutting-edge findings suitable to mobile and molecular services of polyamines in addition to offering the underlying conceptual foundation and information relating to capability healing focusing on polyamines and polyamine metabolism resulting in the improvement of recent healing methods for cancers and .Polyamine transport can follow a dynamin-dependent and clathrin-independent endocytic uptake pathway.

Cell surface heparin sulfate proteoglycans have been implicated in polyamine transport (–), and uptake of polyamines was blocked by a single chain variable fragment antiheparin sulfate antibody. Such uptake mechanisms are covered in.